Common Causes of Chronic Fatigue

Reviewed for accuracy6 min read

Chronic fatigue can stem from a wide range of causes, several of which are commonly overlooked.

Sleep-related causes

Sleep apnea and poor sleep quality are among the most common, and most commonly missed, causes.

Nutrient deficiencies

Low B12, iron, or vitamin D levels can all cause persistent fatigue and are simple to check via bloodwork.

Thyroid issues

An underactive thyroid frequently presents with fatigue as a primary symptom.

Mood-related causes

Depression commonly presents with fatigue, sometimes before mood changes become obvious.

Key takeawayChronic fatigue's most common causes — sleep apnea, nutrient deficiencies, thyroid issues, and mood — are all identifiable through fairly simple bloodwork or a sleep study.
Helpful next steps

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This content is for general educational purposes only and is not a substitute for personalized medical advice. Bloodwork ordered by your doctor is the only way to confirm the underlying cause of fatigue.